A Brooklyn neighborhood’s residential development boom is nearing an end, as a condo tower opens at one of the final sites on the Williamsburg waterfront.

Sales begin Wednesday at One Domino Square, a 39-story tower just north of the Williamsburg Bridge. It’s the sole condo offering in the 11-acre (4.5-hectare) complex that Two Trees Management has been building around the historic Domino Sugar refinery, which was converted into offices.

The tower’s debut is the latest step in the transformation of the onetime industrial area, made possible by a 2005 rezoning that cleared the way for construction of some of Brooklyn’s most expensive housing. Earlier efforts in Williamsburg had been focused closer to the Bedford Avenue L train stop, or farther north along the East River. Two of those waterfront projects — Toll Brothers’ Northside Piers and the Edge by Douglaston Development — were finished in 2007 and 2009, respectively.